All-trans retinoic acid (ATRA) with chemotherapy is the standard of care for acute promyelocytic leukemia (APL), resulting in cure rates exceeding 80%. Pilot studies of treatment with arsenic trioxide ...
Between 1993 and 1998, patients with newly diagnosed APL were eligible based on the following criteria: (1) diagnosis of APL, based on morphological criteria; (2) age 75 years or less; and (3) ...